CHIME (CHemical mIME, pronounced K-IME) is a browser plug-in (works with Netscape and Internet Explorer) that lets you visualize molecules and do simple operations with them, like rotations, translations, getting different coloring and rendering schemes, etc., etc.. You may need the plug-in installed to use it. Just go here, and then let your computer do the rest. You will have to restart your browser for the plug-in to start working.

If you want to learn more abut it, check the CHIME homepage of Eric Mertz, the creator of CHIME. He has tutorials for those bold enough to venture into programming CHIME applets (?). For those who are here to play with the molecules, just point and click...

Aids for protein 3D structure classes

A protein and its 3D structure

• A model of MCP-1, a human chemokine

• alfa helix model
• parallel beta sheet
• antiparallel beta sheet
• beta turn model
• collagen helix (triple polyproline II helix)

• An alfa-alfa corner
• An alfa/alfa toroid motif
• A beta-barrel motif
• A beta propeller motif
• A beta helix pattern
• A beta-alfa-beta motif
• A protein with alfa + beta content

• (1) - (2) - (3) - (4)




PLEASE-PLEASE-PLEASE

Go the the following site. It has a wonderful collection of proteins that can be recalled according to their supersecondary structure motifs. Well worth the effort.

Aids for the Oxygen-binding and transport proteins (Mb and Hb) lectures

Different structures of Myoglobin

• A model of free myoglobin
• Myoglobin bound to oxygen
• Myoglobin bound to carbon monoxide

• Hemoglobin tetramer in the T state
• Hemoglobin tetramer in the R state
• Sickle cell Hemoglobin

X-ray structures of enzymes

Structures of Trypsin

• Free trypsin
• Trypsin bound to substrate
• Model of trypsin and DIPF inhibitor

• Carbonic Anhydrase

• Structure of rhodopsin (photosynthetic reaction center)